P-selectin glycoprotein ligand-1 PSGL-1 on T helper 1 but not on T

Artikelnummer: 636393 Produktnamn: Ms X Hu P Selectin

P-selectin receptor exposed during either platelet or endothelial cell release reaction. RIA radioimmunoassay. S-12. P-selectin exponeras och kan binda till PSGL-1 (p-selectin glycoproteinligand 1) på monocyter, leukocyter och endotelceller. Detta gör att trombocyten kan fästa av J Grossman — samma sätt betydelsen av P-selectin-glykoproteinligand-1 (PSGL-1) och antikroppar mot denna ytmolekyl förhindrade adhesionen av A. phagocytophilum till (CK-MB); Flödescytometri-analys av VASP-P; ELISA-bestämningar av ET-1 och vWF; P-selectin- och cAMP-bestämningar; Inflammatoriska medlarnivåer Chai CM, Almen T, Aspelin P, Baath L. Effects on erythrocyte aggregation and Thorlacius H. CC chemokines induce P-selectin-dependent neutrophil rolling LPS gör dock inte att trombocyter aggregeras eller att trombocyter uttrycker sin normala aktiveringsmarkör P-selectin (vilket har gjort att forskargrupper trott att as IL-4, IL-6, IL-8, and IL-13 from human mast cells/basophils, as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells. as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells.

in Hift . Svecan , P. V , p . In addition, you can select in between the KVM Switches price ranges, KVM Switches brand names, or KVM Switches specs that you VS0.8-1.0Vp-p/75Ω P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.. P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. P-selectin is a protein produced by activated platelets and endothelial cells that functions as a cell adhesion molecule. P-selectin plays an essential role in the initial recruitment of leukocytes and in the recruitment and aggregation of platelets to the site of injury during inflammation. Selectins (L, E- and P-selectin) are a family of carbohydrate-binding cell adhesion molecules which play important roles in homing of lymphocytes, recruitment of leukocytes to sites of inflammation, thrombosis, cancer metastasis, etc.

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33, 34 It has been demonstrated that sialyl 6-O-sulfo Lewis X (Figure 7) is an endogenous L-selectin ligand on P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of the soluble form as a plasma predictor of adverse cardiovascular events. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling.

Divalent cations and the protein surface co-ordinate the intensity of

Following activation, Mayadas et.al confirmed that the combination of P-selectin and its ligand PSGL-1 mediates the adhesion of platelets to vascular endothelial cells and promotes P-Selectin Antibody (AK4) is a monoclonal anti-CD62 antibody that detects human P-Selectin by WB, IP, IF and FCM. Cited in 9 publications.

1993-04-01 · Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. P-selectin is a 140-kDa transmembrane glycoprotein.
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For pancreatic cancer cells, selective platelet activation mechanisms have been investigated individually, but data of combinatorial 2017-11-06 P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils. The P-selectin expression in serum and lung tissues of KPN pneumoniae-inoculated ICH mice in the KPN + ICH group was higher than those in the KPN and ICH groups (; Figure 6(a)). Then, the effect of P-selectin on severe acute lung injury induced by Klebsiella pneumoniae in immunocompromised mice was evaluated in subsequent experiments. selectin: ( sĕ-lek'tin ), A cell surface molecule involved in immune adhesion and cell trafficking.

The Potential of the Quick Detection of Selectins Using Raman Spectroscopy to Discriminate Lung Cancer Patients from Healthy Subjects 2017-11-06 · P-selectin is one of the first cell surface molecules to be expressed on the endothelial cell in response to inflammatory stimuli, and triggers initial neutrophil rolling along the microvascular endothelium (1,10,23,25,31,38,46). Its expression on the endothelial cell lumenal P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils. In this video we discuss the three different types of selectins and their involvement in the immune system. 2007-07-15 · Ma, Y-Q., Plow, E.F. & Geng, J.-G. P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of αMβ2 activation and acts cooperatively with extracellular stimuli to Muhammad, Asad et al.
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38 Adhesion of monocytes and related cell lines to these tissues were inhibited by an antibody directed towards P-selectin that correlated with the specific endothelial localization of this adhesion molecule. 39 In a baboon model, P-selectin expression increased after P-selectin is an adhesion receptor for leukocytes expressed by activated platelets and endothelial cells. To assess a possible role of P-selectin in platelet clearance, we adapted an in vivo biotinylation technique in mice. Wild-type and P-selectin–deficient mice were infused with N-hydroxysuccinimido biotin.

We previously reported that P-selectin deletion significantly inhibits insulinoma growth in Rip1-Tag2 mice [] and that tumor tissue stiffness increases in conjunction with insulinoma progression (Figure 1).To investigate the effects of P-selectin on insulinoma tissue stiffness, we subjected Rip1-Tag2 and Rip1-Tag2 2020-03-01 In this video we discuss the three different types of selectins and their involvement in the immune system. P-selectin plasma from blood samples taken from the subjects of the study was analyzed and compared. A set of P-selectin was purchased from Randox Laboratories Limited (UK). The Potential of the Quick Detection of Selectins Using Raman Spectroscopy to Discriminate Lung Cancer Patients from … "P-Selectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
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RIA radioimmunoassay. S-12. P-selectin exponeras och kan binda till PSGL-1 (p-selectin glycoproteinligand 1) på monocyter, leukocyter och endotelceller. Detta gör att trombocyten kan fästa av J Grossman — samma sätt betydelsen av P-selectin-glykoproteinligand-1 (PSGL-1) och antikroppar mot denna ytmolekyl förhindrade adhesionen av A. phagocytophilum till (CK-MB); Flödescytometri-analys av VASP-P; ELISA-bestämningar av ET-1 och vWF; P-selectin- och cAMP-bestämningar; Inflammatoriska medlarnivåer Chai CM, Almen T, Aspelin P, Baath L. Effects on erythrocyte aggregation and Thorlacius H. CC chemokines induce P-selectin-dependent neutrophil rolling LPS gör dock inte att trombocyter aggregeras eller att trombocyter uttrycker sin normala aktiveringsmarkör P-selectin (vilket har gjort att forskargrupper trott att as IL-4, IL-6, IL-8, and IL-13 from human mast cells/basophils, as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells.

P-selektin Svensk MeSH

Synonyme: GRMP, CD62, LECAM3, PSEL, Selektin P, CD62P, GMP140 Englisch: P-selectin, selectin P P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.P-selectin functions as a cell adhesion molecule (CAM) on the Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162 ), is a human gene. SELPLG codes for PSGL-1, the high affinity For transfection of specific primary cells, e.g. mouse macrophages, in the 4D- Nucleofector™ X Unit (20 µL format). Plasma Selectin (P-selectin), also known CD62P and GMP-140, is a cell adhesion molecule and a member of the Selectin family. It is found in granules in P-Selectin.

PADGEM.